Lets face it, we already broke the theme by letting anything be smokeable. Smoking of drugs was a practice stolen from the new world. The Spanish had no way to describe what they saw upon arrival in the new world. They described it as 'Drinking Smoke'. (Andrew Weil, 1983).
So lets add two stages to the poppy plant after flowering. Wilted & dead.
For a few days after the flowers fall off a poppy pod you can take a tool (Ghetto version is a spoon cut into a quarter moon with teeth) and scrape cuts into the side of the pod (being careful not to breach the inner side of the hull). This is usually done early in the morning and then, in the heat of the midday sun, gatherers will take a wide knife-type tool and scrape the scabs off the pod. This is raw opium. This product can be safely smoked given no other medical factors and appropriate dosing margins for an individuals tolerence (Do your goddamn research before attempting this kind of thing...this is not a fucking tutorial and I am not responsible for your life or inclination to believe everything you read on the goddamn internetz).
This process can be preformed up to eight times per pod by a skilled opium harvester who harvests twice a day. The pod will die within a week tops. At this stage the pod must be cut about a foot below the pod and tied into a pod bundle which is hung to dry for a few weeks or baked-dried at low temperatures (quicker, less risk of fungi) or cured like tobacco in heated barns.
The resultant pod can then be crushed and a chemical or water based extraction can be preformed to create 'cooked' or 'flake' opium. This product can be further refined into morphine, codeine or thebaine (for the synthesis of fentanyl and derivatives). Heroin is made by acetlyzing morphine extractions.
The pod, in the TRADITIONAL fashion was never bled or refined. It was just harvested, dried, crushed and boiled into a tea as has become quite the fad in opiate culture today due to the quasi-legal status of doing so in most countries. Ingesting any drug is by far the least addictive and safest way to consume any drug. If you're interested in more information I will link to a podcast which goes in depth into the history of psychedelic drugs and is a worthwhile lecture to listen to for anyone by the foremost expert on drugs both entheogenic and pharmacological for medical, recreational and spiritual purposes, by Dr. Andrew Weil, given in 1983. You can listen to it on a podcast courtesy of the Psychedelic Salon. Incidentally it is also available as a free podcast via Itunes.
I suspect, however, since we have already violated history and thematics by smoking TOBACCO and weed that however this is implemented shouldn't be to far a cry from the any current thematics.
SO at the very least let's add Pod tea if not the harvesting and smoking of raw opium.
Incidentally which we're talking about tobacco, opium, and weed let's address the addictive factors on a Scale of 1-10. Alcohol, as our baseline is 5. Weed is 1-2, Opium is 3-4 (ingested, 6-7 smoked), tobacco is 10 (smoked, since we don't have sublingual preparations...yet?).
On to...MUSHROOMS!!! Our fungi ancestors. Either Psilocybin or Amenitas can be found througout the northern hemisphere of the globe with dozens of psilocybin varieties and almost half a dozen amenitas. Amenita's are less hallucineogenic and more dissociative leading to otherworldy experiences and contanct with extradimensional beings whereas psilocybin are hallucinogenic and result in epiphanies and revelations about the world we live in.
Btw, if you are unfamiliar with Amenitas think of the Red & White spotted Super Mario Mushrooms. Those are Amenitas. That's right folks. THis is not the first game to implement drug culture references into the play. It's just the first one to do so blatantly.
------I'm not actually suggesting anything....this is just a useless post saying MOAR DURGS PL0X-------
How all that might translate into game effects is a great point of discussion. Feel free to suggest ideas.
I post this not to suggest in game effects & mechanics but to try to give information about real world operations and history in brief so that the inevtiable discussion surrounding these things is not based off misinformation.
I still regret suggesting that hemp be smoked. IMHO marijuana should be an entirely separate plant from hemp like it is in reality.